Population
Individuals carrying different allelic variants of USF1 (fat biopsy samples) and in vitro models
Authors
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Hypothesis-generating for USF1-APOE regulation in hyperlipidemia; does not support practice change.
The study identifies a functional intronic variant in USF1 that regulates APOE expression, providing a mechanistic link to familial combined hyperlipidemia.
Naukkarinen et al. (2005) studied this question.
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