A strain of Pseudomonas aeruginosa (3-Post) was resistant to cefsulodin and ceftazidime at 37 degrees C but sensitive at 20 degrees C. Resistance was mediated by chromosomally-encoded beta lactamase which was synthesised at a high level during growth above 30 degrees C but at a low, inducible level during growth below 27 degrees C.
No takes yet. Share an insight, caveat, or question.
Hewinson et al. (1987) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: