Potential predictive role of Non-HDL to HDL Cholesterol Ratio (NHHR) in MASLD: focus on obese and type 2 diabetic populations

Figures

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  Fig. 1. Flowchart of participants enrollment. Abbreviations: NHANES: the National Health and Nutrition Examination Survey, MASLD: metabolic dysfunction-associated steatotic liver disease, HDL-C: high-density lipoprotein cholesterol, TC: total cholesterol, NHHR: the non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio, PIR: poverty income ratio, BMI: body mass index, WC: waist circumference, HbA1c: glycohemoglobin, ALT: alanine aminotransferase, AST: aspartate aminotransferase

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  Fig. 2. The association between NHHR and MASLD. Each red dot represents the NHHR score level, forming a continuous fitting curve. The area between the blue dashed lines is considered as 95% confidence interval. Age, sex, race/ethnicity, education level, PIR, smoking status, BMI, WC, HbA1c, ALT, AST, GGT, hypertension and T2D were adjusted. Abbreviations: NHHR: the non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio, MASLD: metabolic dysfunction–associated steatotic liver disease, PIR: poverty income ratio, BMI: body mass index, WC: waist circumference, HbA1c: Glycohemoglobin, ALT: alanine aminotransferase, AST: aspartate aminotransferase, GGT: gamma glutamyl transferase, T2D: type 2 diabetes

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  Fig. 3. Subgroup analysis for the association of NHHR and MASLD. Solid red dots represent sample size. The black horizontal line represents 95% confidence interval. Age, sex, race/ethnicity, education level, PIR, smoking status, BMI, WC, HbA1c, ALT, AST, GGT, hypertension and T2D were adjusted (in addition to the stratification factor itself). Abbreviations: PIR: poverty income ratio, BMI: body mass index, WC: waist circumference, HbA1c: Glycohemoglobin, ALT: alanine aminotransferase, AST: aspartate aminotransferase, GGT: gamma glutamyl transferase, T2D: type 2 diabetes