Why the study?
Does polycystic ovary syndrome (PCO) independently alter lipid and lipoprotein profiles in women compared to normal ovulatory women?
Population
76 women, comprising 38 with polycystic ovary syndrome and 38 normal ovulatory women matched for age and…
Comparison
Polycystic ovary syndrome / hyperandrogenaemia… vs Normal ovulatory women matched for age and weight
Design
Case-control
Authors
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Obesity drives HDL reductions in PCO; leaves open whether reproductive hormones independently affect CVD risk.
Does polycystic ovary syndrome (PCO) independently alter lipid and lipoprotein profiles in women compared to normal ovulatory women?
Women with polycystic ovary syndrome have a low to intermediate risk for cardiovascular disease, which is primarily driven by the increased prevalence of obesity rather than reproductive hormone abnormalities.
Graf et al. (1990) studied this question.
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