Why the study?
Does renal transplantation improve left ventricular function in patients with end-stage renal failure and severely impaired LV function?
Does renal transplantation improve left ventricular function in patients with end-stage renal failure and severely impaired LV function?
Severely impaired left ventricular function may dramatically improve after renal transplantation, suggesting it should not preclude isolated renal transplant in favor of combined heart-kidney transplant.
May support isolated renal transplant despite severe LV impairment in ESRD; leaves open generalizability and need for prospective confirmation.
Patients with severely impaired left ventricular function are known to have a poor prognosis. We describe a 20-year-old man with end-stage renal failure, on dialysis, with severely impaired left ventricular function which dramatically improved after renal transplantation. This suggests that poor left ventricular function need not preclude renal transplantation and may, in fact, offer an alternative to combined renal and cardiac transplantation.
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Broek et al. (1991) studied this question.
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