Population
High-risk patients undergoing major operative procedures, particularly orthopedic surgery
Design
Review
Authors
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May support extended prophylaxis decisions in trauma; leaves open prospective validation of pulmonary thrombin generation.
Highlights the systemic nature of post-operative hypercoagulability and the central role of the lungs in thrombin generation, emphasizing the prolonged risk of thromboembolic complications.
Ola E. Dahl (1999) studied this question.
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