Key result
Low-dose heparin resolves TEG-detected hypercoagulability in 100% of extensive hepatic surgery cases.
Why the study?
Extensive hepatic surgery is often associated with coagulopathies that require detection and management of hypercoagulability.
Does thrombelastograph monitoring and targeted heparin administration effectively detect and treat hypercoagulability in patients undergoing extensive hepatic surgery?
Population
19 patients undergoing extensive hepatic surgery
Comparison
Patients with and without hypercoagulability detected by thrombelastograph
Design
Observational case series
Follow-up
During surgery
Authors
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May support TEG monitoring in hepatic surgery; leaves open need for prospective validation.
Observational (n=19)
Does thrombelastograph monitoring and targeted heparin administration effectively detect and treat hypercoagulability in patients undergoing extensive hepatic surgery?
Thrombelastography can effectively detect hypercoagulability during extensive hepatic surgery, allowing for successful management with small doses of heparin.
William S. Howland (1974) conducted an observational in Extensive hepatic surgery (n=19). Heparin sodium was evaluated on Successful treatment of hypercoagulability. Thrombelastography detected hypercoagulability in 9 of 19 patients undergoing extensive hepatic surgery, all of whom were successfully treated with 1,000 to 2,000 units of heparin sodium.
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