Population
mammalian species / skeletal muscle
Design
Review
Authors
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Supports substantial O2 diffusion resistance at the blood-myocyte interface; leaves open its modulation and clinical relevance in cardiovascular disease.
This review highlights that the blood-myocyte interface provides substantial resistance to O2 diffusion, emphasizing the role of erythrocyte hemodynamics in preserving O2 flux during muscle contractions.
Hirai et al. (2018) studied this question.
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