Key result
This review suggests that muscle fiber type recruitment profiles and microcirculation differences may explain the slowing of oxygen uptake kinetics at higher work rates and in chronic diseases.
Understanding the complexities of O2 supply at the capillary-myocyte interface and muscle fiber type differences provides new insights into metabolic control and exercise intolerance in heart failure.
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VO2 kinetics illuminate metabolic control during transitions; leaves open validation of the proposed model in real-world, non-laboratory conditions.
Poole et al. (2008) conducted a review in VO2 kinetics during exercise. This review suggests that muscle fiber type recruitment profiles and microcirculation differences may explain the slowing of oxygen uptake kinetics at higher work rates and in chronic diseases.
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