Why the study?
Does pancreatic islet transplantation or intensive insulin therapy improve pulmonary vascular complications in female Wistar-Furth rats with streptozotocin-induced diabetes?
Population
Female Wistar-Furth rats with long-term streptozotocin (STZ) diabetes
Comparison
Pancreatic islet transplantation or intensive… vs Untreated diabetic animals and non-diabetic…
Design
Preclinical
Authors
Loading...
Islet transplantation may correct diabetic pulmonary vascular shifts in rats unlike insulin; leaves open translation to human pulmonary hypertension.
Does pancreatic islet transplantation or intensive insulin therapy improve pulmonary vascular complications in female Wistar-Furth rats with streptozotocin-induced diabetes?
Pancreatic islet transplantation, unlike intensive insulin therapy, corrects pulmonary vascular resistance shifts in a rat model of streptozotocin-induced diabetes.
Russ et al. (1998) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: