Why the study?
Does insulin replacement improve left ventricle structure and function in a rat model of diabetic cardiomyopathy?
Population
Male Sprague-Dawley rats administered streptozotocin (55 mg/kg i.v.) to induce diabetes, or citrate vehicle
Comparison
Insulin replacement for the final 4 weeks of an… vs Diabetic rats without insulin replacement, and…
Design
Preclinical
Follow-up
8 weeks
Authors
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Insulin replacement ameliorates left ventricular remodeling and diastolic dysfunction in a rat model of early-stage diabetic cardiomyopathy.
Does insulin replacement improve left ventricle structure and function in a rat model of diabetic cardiomyopathy?
Insulin replacement ameliorates left ventricular remodeling and diastolic dysfunction in a rat model of early-stage diabetic cardiomyopathy.
Tate et al. (2017) studied this question.
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