Why the study?
Current antivirals targeting viral proteins risk drug resistance, making targeting host-virus interactions an alternative approach where the RNA-binding protein hnRNPA1 plays an essential role across multiple viruses.
Design
Review
Authors
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Virus-specific hnRNPA1 effects advise selective rather than broad antiviral targeting; leaves open safe translation pending targeted studies.
Key points are not available for this paper at this time.
Kaur et al. (2020) studied this question.