Why the study?
Does two-dimensional speckle tracking echocardiography detect early myocardial damage in young patients with Fabry disease?
Population
66 individuals, comprising 44 young patients with genetically diagnosed Fabry disease and 22 sex-matched…
Comparison
Two-dimensional speckle tracking… vs Healthy volunteers (sex-matched control group).
Design
Cross-sectional
Authors
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May support strain imaging for early Fabry detection before LVH; leaves open prospective validation and outcome impact.
Does two-dimensional speckle tracking echocardiography detect early myocardial damage in young patients with Fabry disease?
Two-dimensional speckle tracking echocardiography can detect subclinical myocardial dysfunction in patients with Fabry disease before the development of left ventricular hypertrophy.
Saccheri et al. (2013) studied this question.
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