Population
trachealis muscle
Comparison
wortmannin and oscillatory strains vs absence of wortmannin / preoscillation state
Design
Preclinical
Authors
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Thick filament recovery after strain in smooth muscle may require cyclic MLC phosphorylation; hypothesis-generating and leaves clinical translation open.
In vivo thick filament reassembly in smooth muscle after mechanical perturbation is facilitated by cyclic MLC phosphorylation associated with repeated stimulation.
Qi et al. (2002) studied this question.
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