Why the study?
Does fosinopril reduce left ventricular wall thickness and improve skeletal muscle blood flow compared to atenolol in patients with essential hypertension?
Does fosinopril reduce left ventricular wall thickness and improve skeletal muscle blood flow compared to atenolol in patients with essential hypertension?
In patients with essential hypertension, treatment with fosinopril, but not atenolol, reduces left ventricular wall thickness, and this regression is associated with enhanced insulin-mediated skeletal muscle blood flow.
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Supports fosinopril over atenolol for LV wall thickness reduction in hypertension; confirms perfusion-cardiac remodeling link.
LARS LIND PER-ERIK ANDERSSON (1998) studied this question.
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