1-Iodo- and 1,4-diiodo-phthalazines were obtained by treating the corresponding chloro compounds with a solution of sodium (or potassium) iodide in acetone containing hydrogen iodide. These iodophthalazines, on reaction with copper cyanide in pyridine, gave the relevant phthalazinecarbonitriles.
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Hirsch et al. (1966) studied this question.
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