Ganging up against the bad guys: Nanofibers of 1 efficiently inhibited the growth of glioblastoma cells but exhibited little acute toxicity toward a neuronal cell line. The selective cytotoxicity probably stems from the Warburg effect of cancer cells and the existence of microtubule-stabilizing proteins in neurons. Supramolecular nanofibers that can interrupt the self-organization of proteins may have potential as nanomedicines for the treatment of cancer.
No takes yet. Share an insight, caveat, or question.
Kuang et al. (2013) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: