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Abstract 1,2-Diketones are readily reduced by fermenting baker’s yeast but the reactions proceed with little selectivity. One notable exception is the reduction of 1-phenyl-1,2-propanedione which affords pure (S)-(−)-2-hydroxy-1-phenyl-1-propanone in good yield.
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Chênevert et al. (1988) studied this question.
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