Why the study?
Does a three-day course of enoxaparin reduce thrombosis in primary total hip replacement patients?
Population
156 primary total hip replacement (THR) patients
Comparison
Enoxaparin at 12 hours preoperatively and 12 and… vs Control group
Design
RCT, Randomisation to either a control group or to receive enoxaparin
Authors
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Supports short-course enoxaparin to reduce calf thrombosis after THA; confirms distal but not proximal DVT prevention.
Does a three-day course of enoxaparin reduce thrombosis in primary total hip replacement patients?
A three-day perioperative course of enoxaparin significantly reduces calf thrombosis compared to control in patients undergoing primary total hip replacement, with increased bruising but no difference in major bleeding.
Warwick et al. (1995) studied this question.
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