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Background: Hepatitis B virus (HBV) is a major global health concern that can cause both acute and chronic liver infection in humans and cause hepatitis B. The main purpose of our investigation was to show the changes in peripheral hematological parameters as a diagnostic biomarker in hepatitis B patients due to HBV compared to healthy controls. Methods: Blood samples from HBV patients already diagnosed by clinicians and healthy subjects were collected from various hospitals in Punjab. The complete blood count (CBC) test and t test were applied to these samples. Result: The hemoglobin (HB), hematopoietic cell transplantation (HCT), mean corpuscular hemoglobin concentration (MCHC), mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH), and neutrophil/lymphocyte ratio (NLR) of patients and controls showed great differences. The white blood cells (WBCs), red blood cells (RBCs), platelets, neutrophils, lymphocytes, monocytes, and eosinophils in hepatitis B patients showed no association. Conclusion: Our primary results indicate a promising biomarker to monitor HBV infection by using information from hematological parameters. Further large cohort investigations are required for more accurate results.
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Rasheed et al. (2022) studied this question.
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