Why the study?
How do pulmonary mechanics change following open-heart surgery for acquired valvular disease?
How do pulmonary mechanics change following open-heart surgery for acquired valvular disease?
Significant deterioration in pulmonary mechanics, specifically decreased compliance and increased work of breathing, is associated with fatal outcomes following open-heart surgery for valvular disease.
Postoperative decline in compliance with rising work of breathing was associated with fatality after valvular surgery; hypothesis-generating for prospective monitoring trials.
Pulmonary mechanics were determined preoperatively and postoperatively in 20 patients following open-heart surgery for acquired valvular disease. 2. The surviving patients had minimal increase of the work of breathing, associated with an increase in nonelastic resistance during the early postoperative period. These changes in pulmonary mechanics are insufficient to explain the respiratory difficulties experienced by these patients. 3. In the fatal cases compliance decreased to half the preoperative level, and respiratory work increased to five times the preoperative value. In these individuals excessive work of breathing produces a significant demand on physiological resources, and controlled mechanical ventilation is indicated.
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Garzon et al. (1966) studied this question.
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