Why the study?
Prompt evaluation of anti-Xa activity is important during life-threatening bleeding, urgent surgery, or acute thromboembolism under LMWH treatment, requiring a simple point-of-care detection method.
Does a modified viscoelastic point-of-care method reliably detect enoxaparin levels compared to standard anti-Xa activity in patients on enoxaparin?
Comparison
Viscoelastometric RVV-test on ClotPro vs chromogenic anti-Xa activity
Design
Single-centre observational study
Authors
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May enable rapid bedside enoxaparin assessment in emergencies; leaves open prospective validation before clinical adoption.
Does a modified viscoelastic point-of-care method reliably detect enoxaparin levels compared to standard anti-Xa activity in patients on enoxaparin?
A modified viscoelastic point-of-care method using RVV clotting time ratios can provide rapid, semiquantitative estimation of enoxaparin anti-Xa activity within 10 minutes.
Hajdú et al. (2025) studied this question.
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