Why the study?
Does breathing 100% oxygen affect ventilation and circulation in new-born lambs before and after carotid chemoreceptor denervation?
Does breathing 100% oxygen affect ventilation and circulation in new-born lambs before and after carotid chemoreceptor denervation?
The study demonstrates that new-born lambs have a significant hypoxic drive to ventilation mediated by functioning and mature peripheral chemoreceptors.
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Hyperoxia suppresses ventilation via carotid chemoreceptors in newborn lambs; confirms peripheral drive but leaves human translation open.
M. J. Purves (1966) studied this question.
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