Why the study?
Adult mammalian hearts lack the capacity to appreciably regenerate cardiomyocytes after injury, making the promotion of cardiomyocyte proliferation to reinitiate regeneration and suppress heart failure a key research goal.
Design
Review
Authors
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No immediate practice change for post-injury repair; leaves open targeted trials to validate proliferation-based strategies.
Key points are not available for this paper at this time.
Li et al. (2021) studied this question.
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