Why the study?
Are anti-myocardial autoantibodies more prevalent in patients with idiopathic dilated cardiomyopathy compared to healthy controls, and do they correlate with clinical profiles?
Population
100 Japanese patients with idiopathic dilated cardiomyopathy and 100 age-matched healthy control subjects
Comparison
Screening for anti-myocardial autoantibodies… vs Age-matched healthy control subjects
Design
Case-control
Authors
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AMCA positivity may flag higher arrhythmic risk in IDC but should not yet change practice; leaves open causal role and need for prospective trials.
Are anti-myocardial autoantibodies more prevalent in patients with idiopathic dilated cardiomyopathy compared to healthy controls, and do they correlate with clinical profiles?
Anti-myocardial autoantibodies are frequently detected in patients with idiopathic dilated cardiomyopathy and correlate with adverse clinical profiles such as non-sustained ventricular tachycardia and increased left ventricular dimensions.
Baba et al. (2001) studied this question.
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