Why the study?
Does propofol, sevoflurane, or desflurane cause persistent hemodynamic compromise during recovery in an open-chest rabbit model?
Population
Anesthetized, open-chest New Zealand White rabbits
Comparison
Propofol, sevoflurane, and desflurane vs Time-matched controls
Design
Preclinical
Follow-up
30-min recovery period
Authors
Loading...
Persistent propofol effects in rabbit recovery suggest caution with its use; animal data leave open human translation versus volatiles.
Does propofol, sevoflurane, or desflurane cause persistent hemodynamic compromise during recovery in an open-chest rabbit model?
In a rabbit model, propofol causes persistent depression of cardiovascular function during recovery compared to the rapid recovery seen with sevoflurane and desflurane.
Royse et al. (2008) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: