Changes in Left Ventricular Global Longitudinal Strain Before and After Balloon Mitral Valvuloplasty

Background: Several studies have reported left ventricular systolic dysfunction as measured by the global longitudinal strain (GLS) in patients with mitral stenosis. This study aims to determine left ventricular systolic function changes using global longitudinal strain early after balloon mitral valvuloplasty (BMV) and on long-term observation. Methods: Baseline echocardiography data and GLS were taken before BMV, followed up early after (2 to 7 days), and in the long-term (6 months to 1 year) after BMV. Result: Among 36 patients, the mean age was 43.41±10.04 y.o, female dominant (72%); the majority have atrial fibrillation (56%), with a median mitral valve area (MVA) before BMV of 0.6 (0.2-1.3) cm2 and mean mitral valve gradient before BMV of 12.95 ± 5.29 mmHg. GLS increased from -14.34 ± 3.05% to 15.84 ±3.11% and increased further to -17.29 ± 2.80% (p<0.05), at pre-BMV- early post-BMV, and long-term follow up, respectively. Conclusions: There is a significant improvement in LV GLS early after BMV compare to baseline. The GLS improved further at long-term evaluation (six months until one year) after BMV.