Why the study?
Does terazosin reduce blood pressure and alter urinary dopamine excretion in untreated hypertensive patients?
Population
24 untreated hypertensive patients
Comparison
Terazosin 2-4 mg/day for 4 weeks vs Placebo for 4 weeks
Design
RCT, Double-blind
Follow-up
4 weeks
Authors
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Supports terazosin for BP lowering in untreated hypertension; extends evidence by linking efficacy to reduced urinary dopamine excretion.
Does terazosin reduce blood pressure and alter urinary dopamine excretion in untreated hypertensive patients?
Terazosin effectively lowers blood pressure and reduces urinary dopamine excretion in untreated hypertensive patients over 4 weeks.
Romero et al. (1992) studied this question.
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