Population
Anesthetized, immobilized, and artificially ventilated rabbits
Comparison
Changes in blood gas composition and central… vs Baseline states; non-vagotomized state for vagus…
Design
Preclinical
Authors
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Animal data on regional sympathetic responses to hypoxia are hypothesis-generating; leaves open translation to human cardiovascular control.
Different sympathetic efferents show distinct regional response patterns to moderate hypoxia, hypercapnia, and thermal stimulation, which become generalized under extreme hypoxia.
Iriki et al. (1972) studied this question.
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