Recurrent Intravascular Coagulation with Renal Cortical Necrosis and Recovery

Case Studies1 March 1966Recurrent Intravascular Coagulation with Renal Cortical Necrosis and RecoveryP. W. STRAUB, M.D., A. VON FELTEN, M.D., P. G. FRICK, M.D., PH.D.P. W. STRAUB, M.D.Search for more papers by this author, A. VON FELTEN, M.D.Search for more papers by this author, P. G. FRICK, M.D., PH.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-64-3-643 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptAcquired hypofibrinogenemia is due either to a decreased rate of fibrinogen production in the liver or to an increased rate of disappearance from the circulating blood. The latter mechanism can be the result of intravascular coagulation or accelerated fibrinolysis. Whereas the development of thrombolytic therapy has introduced a unique tool for investigation of pure fibrinolytic states, it is not possible to induce intravascular coagulation experimentally in man. Progress in the basic understanding of this condition is therefore dependent on careful investigation of human cases of acquired hypofibrinogenemia.The case reported below is an example of acquired acute hypofibrinogenemia in a...References1. DUCKERT F: Le diagnostic des coagulopathies, in Eight Colloquia on Clinical Pathology. Presses Académiques Européennes, Brussels, 1958, p. 635. Google Scholar2. CLAUSS A: Gerinnungsphysiologische Schnell-methode zur Bestimmung des Fibrinogens. Acta Haemat. (Basel) 17: 237, 1957. CrossrefMedlineGoogle Scholar3. HARTERT H: Die Thrombelastographie. Z. Ges. Exp. Med. 117: 189, 1951. CrossrefMedlineGoogle Scholar4. ASTRUPMÜLLERTZ TS: The fibrin plate method for estimating fibrinolytic activity. Arch. Biochem. 40: 346, 1952. 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ALBREYSIMMONS JART: The use of a papain solution of approximately pH 3.0 in Rh testing and atypical antibody detection. Med. J. Aust. 47: 210, 1960. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Zürich, SwitzerlandFrom the Department of Medicine, Kantonsspital, University of Zürich, Zürich, Switzerland.Requests for reprints should be addressed to Paul G. Frick, M.D., Kantonsspital, University of Zürich, 8006 Zürich, Switzerland. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByRenal disease in pregnancyEFFECTS OF NEOPLASMS ON RENAL ELECTROLYTE FUNCTIONDiagnostic procedures and long-term prognosis in bilateral renal cortical necrosisAcute renal failure in obstetric septic shockCase 32-1972ReferenceReptilase®-R—A New Reagent in Blood CoagulationHigh Molecular Weight Derivatives of Human Fibrinogen Produced by PlasminHemolytic-Uremic Syndrome in Older Children and AdultsRecognition and treatment of intravascular coagulationHÆMOLYTIC-URÆMIC SYNDROMEETHICAL AND SOCIAL ASPECTS OF TREATMENT OF SPINA BIFIDARenal cortical necrosis and right nephrectomy, with survival, in a man 1 March 1966Volume 64, Issue 3Page: 643-654KeywordsBloodFibrinogenFibrinolysisLiverNecrosis Issue Published: 1 March 1966 PDF DownloadLoading ...