Why the study?
Does intravenous Escherichia coli endotoxin decrease physiologic variability in healthy human volunteers?
Does intravenous Escherichia coli endotoxin decrease physiologic variability in healthy human volunteers?
Systemic inflammation induced by endotoxemia leads to a generalized decrease in physiologic variability across divergent organ systems.
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Endotoxemia may reduce physiologic variability across systems; hypothesis-generating for entropy metrics in sepsis monitoring, pending validation.
Rassias et al. (2005) studied this question.
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