Why the study?
Does the carotid baroreflex control renin release in anesthetized dogs, and how do vagal afferents and renal arterial pressure affect this?
Population
10 anesthetized dogs with aortic nerves sectioned
Comparison
Reduction of pressure in vascularly isolated… vs Baseline states or conditions where renal…
Design
Preclinical
Authors
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Supports baroreflex-mediated renin control in dogs; leaves open translation to human cardiovascular disease.
Does the carotid baroreflex control renin release in anesthetized dogs, and how do vagal afferents and renal arterial pressure affect this?
The carotid baroreflex is involved in the neural control of renin release, but this reflex can be suppressed by activation of cardiopulmonary receptors or a rise in renal arterial pressure.
Jarecki et al. (1978) studied this question.
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