Why the study?
Does rivaroxaban reduce symptomatic VTE compared to enoxaparin in patients after total hip or knee arthroplasty?
Population
Patients undergoing total hip arthroplasty (THA) or total knee arthroplasty (TKA) (9 RCTs)
Comparison
Rivaroxaban vs Enoxaparin
Design
Meta-analysis
Authors
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Supports rivaroxaban over enoxaparin for post-arthroplasty VTE prevention with bleeding caution; confirms RCT efficacy in meta-analysis.
Does rivaroxaban reduce symptomatic VTE compared to enoxaparin in patients after total hip or knee arthroplasty?
Rivaroxaban is more effective than enoxaparin for preventing symptomatic DVT after hip or knee arthroplasty, but it increases the risk of major bleeding.
Ning et al. (2016) studied this question.
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