Why the study?
Doppler echocardiography is commonly used in congenital heart disease, but its accuracy in estimating systolic pulmonary artery pressure in pediatric patients required evaluation.
Does Doppler echocardiography accurately estimate systolic pulmonary artery pressure compared to right heart catheterization in pediatric patients with congenital heart disease?
Does Doppler echocardiography accurately estimate systolic pulmonary artery pressure compared to right heart catheterization in pediatric patients with congenital heart disease?
Doppler echocardiography significantly underestimates systolic pulmonary artery pressure compared to right heart catheterization in pediatric patients with congenital heart disease, with only 57.5% of measurements considered accurate.
Background: Doppler echocardiography (D-ECHO) is a commonly used imaging tool for both diagnosis and follow-up examination of congenital heart disease (CHD). The goal of this study is to evaluate the accuracy of D-ECHO as used to measure an estimate sPAP in pediatric patients with CHD. Methods: A prospective study in 397 pediatric patients with CHD has been carried out to compare estimate sPAP measured with D-ECHO to that measured with right heart catheterization (RHC). Pearson correlation analyses were used to calculate the correlation coefficients between RHC and D-ECHO. Bland-Altman analyses were carried out to assess the agreement between the two methods. Results: Our data have demonstrated a significant underestimation of sPAP by DECHO compared to that by RHC. A strong correlation (r = 0.957, p < 0.01) was found between sPAP (36.1±14.9 mmHg) and RVSP (36.0±14.5 mmHg) measured with RHC. However, a relatively weak correlation (r = 0.219, p < 0.01) was observed between sPAP (36.1 ± 14.9 mmHg) measured during RHC and sPAP (28.7±9.7 mmHg) as estimated using D-ECHO. The Bland-Altman analysis demonstrated that the bias for D-ECHO sPAP estimates was 6.6 mmHg with 95% limits of agreement ranging from - 23.6 mmHg to 36.8 mmHg. A total of 57.5% of D-ECHO measurements were found to be accurate, with accuracy predefined as 95% of agreement within ±10 mmHg for sPAP estimates
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Yin et al. (2019) studied this question.
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