Surface label experiments using the galactose oxidase-]3H]-borohydride technique reveal that cells from drug-resistant Chinese hamster ovary clones possess a surface carbohydrate component of apparent molecular weight 165,000 which is absent from wild-type cells. The component may also be demonstrated by [14C]glucosamine incorporation but not by [3H]leucine incorporation or by the lactoperoxidase surface labeling reaction.
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Juliano et al. (1976) studied this question.
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