What question did this study set out to answer?

To describe the clinical course, acute mortality, and long-term pulmonary sequelae associated with adenovirus type 21 pneumonitis in young children.

January 11, 1969BMJOpen Access

Bronchopneumonia with Serious Sequelae in Children with Evidence of Adenovirus Type 21 Infection

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Authors

WLWilliam LangBioMarin (United States)CHColin W. HowdenUniversity of Tennessee at Knoxville JBJohn BurtonThe University of Queensland

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Implication

Observational study reports severe lung damage following adenovirus type 21 infection in young children, highlighting long-term respiratory sequelae like bronchiectasis.

Key Points

To describe the clinical course, acute mortality, and long-term pulmonary sequelae associated with adenovirus type 21 pneumonitis in young children.
Retrospective clinical case series evaluating 25 young children aged 3 to 18 months presenting with severe pneumonitis in Auckland, New Zealand, in 1965.
Assessed virological recovery of adenovirus type 21 alongside acute clinical outcomes and subsequent development of chronic pulmonary pathology.
Two of the 25 pediatric patients died during the acute disease episode.
Among survivors, 60% exhibited permanent lung damage, considered secondary to obliterative bronchiolitis.
Proven bronchiectasis developed in 20% of the surviving children during follow-up.

Cite This Study

Lang et al. (1969) studied this question.

synapsesocial.com/papers/6a85598a8018c50ef23d9b2b https://doi.org/10.1136/bmj.1.5636.73

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Implication

Observational study reports severe lung damage following adenovirus type 21 infection in young children, highlighting long-term respiratory sequelae like bronchiectasis.

Bronchopneumonia with Serious Sequelae in Children with Evidence of Adenovirus Type 21 Infection

Discussion

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Implication

Key Points

Cite This Study

Bronchopneumonia with Serious Sequelae in Children with Evidence of Adenovirus Type 21 Infection

Discussion

Member takes

Implication

Key Points

Cite This Study

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