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May 1, 1994Journal of Biomechanical Engineering

LDA Measurements of Mean Velocity and Reynolds Stress Fields Within an Artificial Heart Ventricle

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Population

Penn State 70 cc electric artificial heart/ventricular assist device (in vitro model)

Design

Preclinical

Authors

JBJ.T. BaldwinSDSteven DeutschDGDavid B. Geselowitz

Discussion

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Overview

Supports prioritizing valve design over chambers to limit high-stress jets in artificial hearts; hypothesis-generating for human hemolysis reduction.

Structured PICO

P
Population
Penn State 70 cc electric artificial heart/ventricular assist device (in vitro model)
I
Intervention
Laser Doppler Anemometry measurements at 140 locations at 8 times during the cardiac cycle
O
Outcome
Mean (ensemble average) velocities and turbulent (Reynolds) stressessurrogate

Fluid mechanics improvements in artificial hearts should focus on valve design and pump operating conditions rather than pumping chamber design, as high turbulent stresses are localized to regurgitant jets.

Cite This Study

Baldwin et al. (1994) studied this question.

synapsesocial.com/papers/6a855cb035bc0eada8d59899https://doi.org/10.1115/1.2895719
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Pulsed Ultrasonic Doppler Velocity Measurements Inside a Left Ventricular Assist Device1986 · 40 citations
  2. 2Two-Component Laser Velocimeter Measurements Downstream of Heart Valve Prostheses in Pulsatile Flow1986 · 30 citations
  3. 3Unsteady Fluid Dynamics of Several Mechanical Prosthetic Heart Valves Using a Two Component Laser Doppler Anemometer System1997 · 15 citations
  4. 4Fluid Stresses in the Vicinity of Disk, Ball, and Tilting Disk Prosthetic Heart Valves From In-Vitro Measurements1977 · 23 citations
  5. 5Velocity and Shear Stress Distribution Downstream of Mechanical Heart Valves in Pulsatile Flow1989 · 33 citations