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March 1, 1982Acta Physiologica Scandinavica

Impairment during marked hypotension of the plasma volume control in hemorrhage

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Population

Cats (preclinical model)

Design

Preclinical

Authors

JLJ. LUNDVALLMalmö UniversityDGDavid GustafssonSwedish Meteorological and Hydrological Institute

Discussion

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Implication

Severe hypotension may inactivate fluid compensation and worsen shock; leaves open human relevance and therapeutic targeting.

Structured PICO

P
Population
Cats (preclinical model)
I
Intervention
Pronounced hypovolemia leading to hypotension levels of 30-40 mmHg (hemorrhage)
O
Outcome
Fluid transfer from skeletal muscle to blood (plasma volume regulation)surrogate

During severe hemorrhage with marked hypotension (30-40 mmHg), the vital compensatory mechanism of fluid transfer from skeletal muscle to blood is inactivated, which may compromise survival.

Cite This Study

LUNDVALL et al. (1982) studied this question.

synapsesocial.com/papers/6a855e1067f5f0039bad93fahttps://doi.org/10.1111/j.1748-1716.1982.tb06997.x
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Mechanism of volume replacement and vascular constriction following hemorrhage1965 · 72 citations
  2. 2Hormonal and neurogenic adrenergic control of the fluid transfer from skeletal muscle to blood during hemorrhage1981 · 20 citations
  3. 3Regional Distribution of Circulating Blood During Submersion Asphyxia in the Duck1964 · 238 citations
  4. 4Fluid transfer from skeletal muscle to blood during hemorrhage Importance of beta adrenergic vascular mechanisms1978 · 42 citations
  5. 5Osmotic Fluid Transfer from Tissue to Blood during Hemorrhagic Hypotension1973 · 74 citations