Population
Skeletal muscle model undergoing hemorrhagic hypotension
Design
Preclinical
Authors
Loading...
May signal decompensation risk in prolonged hemorrhage; leaves open translation of local dilator mechanisms to humans.
During prolonged hemorrhage, the initial compensatory reflex vascular constriction in skeletal muscle gradually declines due to local dilator factors, leading to detrimental fluid filtration in later stages.
Lundoren et al. (1964) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: