What question did this study set out to answer?

To evaluate the correlation between the luteinising hormone-to-follicle-stimulating hormone (LH/FSH) ratio and hypovitaminosis D as a predictor of unexplained infertility in women.

August 19, 2026Nigerian Postgraduate Medical JournalOpen Access

Luteinising Hormone-to-follicle-stimulating Hormone Ratio for Predicting Unexplained Infertility in Patients with Hypovitaminosis D

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Authors

WHWalid Hassene HamriUniversité Mustapha Stambouli de Mascara FCFatima ChenniUniversité Djilali de Sidi Bel Abbès CMChahnez Hadj Slimane MiraliUniversity Ferhat Abbas of Setif

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Implication

Cross-sectional study finds elevated LH/FSH ratio predicts unexplained infertility in women with hypovitaminosis D, highlighting its utility as a biomarker for reproductive health.

Key Points

To evaluate the correlation between the luteinising hormone-to-follicle-stimulating hormone (LH/FSH) ratio and hypovitaminosis D as a predictor of unexplained infertility in women.
Retrospective cross-sectional study of N=200 women aged 18–47 years evaluated between January 2023 and December 2024 at a single fertility center in Algeria.
Patients were categorized into vitamin D deficient, insufficient, and sufficient groups to assess serum hormone levels and reproductive parameters.
Hypovitaminosis D was present in 44.5% of patients, and the LH/FSH ratio was significantly higher in the deficient group (1.67 ± 1.88) compared to the insufficient (0.94 ± 0.59) and sufficient groups (1.02 ± 0.64; P = 0.018).
Patients in the fourth quartile of the LH/FSH ratio had significantly higher odds of vitamin D deficiency or insufficiency (OR = 11.37, 95% CI: 4.13–22.00, P = 0.021).
The LH/FSH ratio demonstrated a diagnostic accuracy of 0.724 as a predictor for unexplained infertility.

Cite This Study

Hamri et al. (2026) studied this question.

synapsesocial.com/papers/6a85636403308d306e2d67a2 https://doi.org/10.4103/npmj.npmj_638_25

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Implication

Cross-sectional study finds elevated LH/FSH ratio predicts unexplained infertility in women with hypovitaminosis D, highlighting its utility as a biomarker for reproductive health.

Luteinising Hormone-to-follicle-stimulating Hormone Ratio for Predicting Unexplained Infertility in Patients with Hypovitaminosis D

Discussion

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Implication

Key Points

Cite This Study

Luteinising Hormone-to-follicle-stimulating Hormone Ratio for Predicting Unexplained Infertility in Patients with Hypovitaminosis D

Discussion

Member takes

Implication

Key Points

Cite This Study

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