Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
August 16, 2026BMC Endocrine DisordersOpen Access

Association between vitamin D levels, hormonal profile, and ovarian reserve in infertile women

View Full Paper
Ask AI
Bookmark
Share

Authors

MKMaryam Azizi KutenaeeHormozgan University of Medical SciencesNRNasibeh RoozbehHormozgan University of Medical SciencesETElaheh TaghvaeiHormozgan University of Medical Sciences

Discussion

Loading...

Member takes

Implication

Cross-sectional study finds low vitamin D links to higher BMI and reduced LH in infertile women, suggesting metabolic and endocrine interactions in reproductive health.

Key Points

  • To evaluate how circulating serum vitamin D levels relate to reproductive hormone profiles and ovarian reserve markers in infertile women.
  • Conducted a retrospective cross-sectional analysis of medical records from 880 infertile women aged 18–45 years.
  • Stratified participants by serum vitamin D status into sufficient (≥30 ng/mL), insufficient (21–29 ng/mL), and deficient (≤20 ng/mL) groups.
  • Analyzed hormonal factors (FSH, LH, AMH, E2, TSH) and antral follicle count (AFC) using Kruskal-Wallis tests and multinomial logistic regression models.
  • Nearly half of participants (47.4%) were vitamin D deficient, exhibiting significantly higher BMI values and lower LH concentrations than vitamin D-sufficient women (p < 0.05).
  • Multinomial logistic regression showed BMI positively predicted vitamin D insufficiency (OR = 1.045, p = 0.029) and deficiency (OR = 1.058, p = 0.001), whereas LH was inversely associated with deficiency (OR = 0.964, p = 0.040).
  • Adjusted regression models showed higher AMH was associated with vitamin D insufficiency, but showed no significant association with vitamin D deficiency.

Cite This Study

Kutenaee et al. (2026) studied this question.

synapsesocial.com/papers/6a817a11f2fb91fc834adac6https://doi.org/10.1186/s12902-026-02500-x
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The Correlation Between Serum Levels of 25-OH Vitamin D and Ovarian Reserve Parameters in Infertile Women2024 · 2 citations
  2. 2VITAMIN D AND INFERTILITY: A CASE-CONTROL STUDY CONDUCTED IN BAGHDAD CITY2026
  3. 3Luteinising Hormone-to-follicle-stimulating Hormone Ratio for Predicting Unexplained Infertility in Patients with Hypovitaminosis D2026
  4. 4Prevalence and Determinants of Low Serum Vitamin D Among Women Attending Infertility Clinics in Japan: A Real‐World Multicenter Cross‐Sectional Study2026 · 1 citations
  5. 5Assessment of Vitamin D Levels in Infertile Females - A Tertiary Care Hospital Experience2024