Evaluation of the Correlation of Arterial and Venous Lactate and Glucose Concentrations in Anesthetized Critically Ill Dogs

Francesca Tirillini; H. de Rooster; Ingeborgh Polis; Nausikaa Devriendt

doi:10.1111/vec.70141

August 16, 2026Journal of Veterinary Emergency and Critical Care

Evaluation of the Correlation of Arterial and Venous Lactate and Glucose Concentrations in Anesthetized Critically Ill Dogs

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Key Points

To assess the correlation between arterial and venous lactate and glucose levels and examine the relationship between hyperlactatemia and hyperglycemia in critically ill dogs.
Prospective clinical study of N=90 client-owned dogs presenting for emergency surgery at a university veterinary teaching hospital (June 2015 to March 2024).
Paired blood samples from the dorsal pedal artery and jugular vein were collected ≤5 minutes apart and analyzed using portable devices; dogs with diabetes mellitus were excluded.
Arterial and venous measurements correlated strongly for both lactate (ρ = 0.850, 95% CI: 0.766–0.905, p < 0.001) and glucose (ρ = 0.970, 95% CI: 0.950–0.982, p < 0.001).
Venous lactate demonstrated 81.8% sensitivity and 88.6% specificity for detecting arterial hyperlactatemia, with correlation being stronger in hyperlactatemic dogs (ρ = 0.835) than normolactatemic dogs (ρ = 0.488).
Arterial lactate and glucose concentrations displayed no significant correlation (ρ = -0.57, 95% CI: -0.261 to -0.152, p = 0.593).

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Implication

Prospective clinical study demonstrates strong correlation between arterial and venous lactate and glucose in critically ill dogs, suggesting venous sampling is a reliable emergency alternative.

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Tirillini et al. (2026) studied this question.

synapsesocial.com/papers/6a85639d03308d306e2d6e37 https://doi.org/10.1111/vec.70141

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Evaluation of the Correlation of Arterial and Venous Lactate and Glucose Concentrations in Anesthetized Critically Ill Dogs

Key Points

No abstract yet

Implication

Discussion

Cite This Study

Evaluation of the Correlation of Arterial and Venous Lactate and Glucose Concentrations in Anesthetized Critically Ill Dogs

Key Points

No abstract yet

Implication

Discussion

Cite This Study

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