What question did this study set out to answer?

To evaluate strategies for overcoming barriers in the hepatitis C care cascade by translating successful structural and clinical models from the HIV epidemic.

August 19, 2026Journal of General Internal MedicineOpen Access

Meeting Patients with Hepatitis C Where They Are: Lessons from the HIV Epidemic in the USA

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Authors

ASAnna ScialliUniversity of California, Los Angeles TVTara VijayanUniversity of California, Los Angeles

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Implication

Narrative review highlights persistent barriers to hepatitis C elimination in vulnerable populations, indicating that HIV-informed care models can dramatically improve treatment access.

Key Points

To evaluate strategies for overcoming barriers in the hepatitis C care cascade by translating successful structural and clinical models from the HIV epidemic.
Reviewed structural, payor, and provider-level barriers limiting direct-acting antiviral uptake in the United States.
Synthesized public health interventions and harm-reduction frameworks established during the HIV epidemic to identify applicable solutions for hepatitis C virus elimination.
Identified that acute hepatitis C infections continue to rise despite curative direct-acting antivirals, driven by payor restrictions and provider hesitance to treat people who use drugs.
Demonstrated that reframing adherence as a need for supportive services rather than a prerequisite for therapy improves treatment completion among marginalized groups.
Proposed actionable HIV-informed interventions for hepatitis C, including rapid inpatient test-and-treat protocols and expanded community-based testing.

Cite This Study

Scialli et al. (2026) studied this question.

synapsesocial.com/papers/6a85642503308d306e2d7b81 https://doi.org/10.1007/s11606-026-10629-7

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Implication

Narrative review highlights persistent barriers to hepatitis C elimination in vulnerable populations, indicating that HIV-informed care models can dramatically improve treatment access.

Meeting Patients with Hepatitis C Where They Are: Lessons from the HIV Epidemic in the USA

Discussion

Member takes

Implication

Key Points

Cite This Study

Meeting Patients with Hepatitis C Where They Are: Lessons from the HIV Epidemic in the USA

Discussion

Member takes

Implication

Key Points

Cite This Study

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