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August 19, 2026Journal of Racial and Ethnic Health DisparitiesOpen Access

Beyond Appendicitis: A Retrospective Study Predicting Appendiceal Neoplasms in the Era of Non-Operative Management in Jamaica

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Authors

OTO’Rane D. ThomasRTRory ThompsonSJScott S. P. Jennings

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Overview

Retrospective cohort study identifies clinical predictors of appendiceal neoplasms in acute appendicitis, suggesting criteria to safely guide non-operative management decisions.

Key Points

  • To determine the prevalence and identify independent demographic, clinical, laboratory, and radiological predictors of appendiceal neoplasms among patients undergoing surgery for acute appendicitis.
  • Conducted a retrospective cohort study of consecutive patients (N=441) who underwent appendicectomy for acute appendicitis at the University Hospital of the West Indies between January 2016 and December 2020.
  • Evaluated predictors of neoplasms using bivariate analyses and Firth's logistic regression models.
  • Appendiceal neoplasms were identified in 2.72% (12/441) of patients, with low-grade appendiceal mucinous neoplasm being the most common subtype (6/12 cases).
  • Independent predictors of neoplasm were age > 30 years (OR = 9.12; 95% CI, 1.65–50.52; p = 0.011), atypical abdominal pain (OR = 4.08; 95% CI, 1.32–12.65; p = 0.015), absolute neutrophil count < 10 × 10^9/L (OR = 4.16; 95% CI, 1.03–16.75; p = 0.045), and appendiceal diameter > 15 mm (OR = 5.49; 95% CI, 1.5–20.05; p = 0.010).

Cite This Study

Thomas et al. (2026) studied this question.

synapsesocial.com/papers/6a85642503308d306e2d7bcfhttps://doi.org/10.1007/s40615-026-03153-1
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Retrospective analysis of the incidence of appendiceal neoplasm and malignancy in patients treated for suspected acute appendicitis2024 · 10 citations
  2. 2Oncologic Risk of Missed Appendiceal Tumors in Acute Appendicitis2026 · 4 citations
  3. 3Risk of appendiceal cancer in patients undergoing appendectomy for appendicitis in the era of increasing nonoperative management2019 · 43 citations
  4. 4Incidence of malignancy in appendiceal surgical specimens: A retrospective single-center study2026
  5. 5Clinicopathological Profile and Management of Appendiceal Neoplasm: An Observational Study2025