Amiodarone can cause acute pulmonary toxicity and ARDS even after a short course of treatment, particularly following lung resection.
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Clinicians should monitor for early amiodarone toxicity after lung resection; this case leaves open incidence and risk factors.
Amiodarone-induced pulmonary toxicity has been described mostly in patients receiving large doses of the drug over prolonged periods. In this report, we describe the early onset of acute pulmonary toxicity leading to acute respiratory distress syndrome after a short course of amiodarone treatment following middle-lobe non-small-cell lung cancer resection.
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Handschin et al. (2003) studied this question.
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