Why the study?
What are the neurological complications associated with thrombolytic treatment in patients with acute myocardial infarction?
What are the neurological complications associated with thrombolytic treatment in patients with acute myocardial infarction?
Thrombolytic treatment for acute myocardial infarction is associated with a 2.58% rate of neurological complications, including previously undescribed seizures during infusion.
Supports vigilant neurological monitoring during AMI thrombolysis; leaves open whether infusion-related seizures warrant targeted prospective study.
We examined 348 patients who underwent thrombolytic treatment for acute myocardial infarction. Nine patients (2.58%) developed neurological complications related directly or indirectly to this procedure. Cerebral hemorrhage occurred in 3 patients; 2 patients had transient ischemic attacks, 1 had syncope, another had psychomotor agitation and 2 patients presented seizures during the infusion of the thrombolytic agent, without hemodynamic abnormalities. This latter feature had never been described before.
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Caramelli et al. (2009) studied this question.
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