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Editorial commentary reviews the discovery of the bacterium causing Legionnaires' disease in outbreak cohorts, highlighting the resolution of previous unexplained respiratory epidemics.
Editorials1 April 1979Legionnaires' Disease: They Came, Saw, and ConqueredMAXWELL FINLAND, M.D.MAXWELL FINLAND, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-90-4-710 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptIn the 1 December 1977 issue ofThe New England Journal of Medicine, Fraser and coworkers from the Center for Disease Control (CDC) presented their report of the now famous Philadelphia epidemic of Legionnaires' disease, of which the onset of the first recognized case was 20 July 1976, an interval of about 16 months before the publication date of their paper (1). The details of the isolation of the causative bacterium, its role in two earlier unexplained epidemics of respiratory disease—one in the District of Columbia in 1965 and the other in Pontiac, Michigan, in 1968—and its demonstration in tissues...References1. FRASERTSAIORENSTEINPARKINBEECHAMSHARRARHARRISMALLISONMARTINMCDADESHEPARDBRACHMAN DTWWHRJGSJCP: Legionnaires' disease. Description of an epidemic of pneumonia. N Engl J Med 297:1189-1197, 1977 CrossrefMedlineGoogle Scholar2. MCDADESHEPARDFRASERTSAIREDUSDOWDLE JCDTMW: Legionnaires' disease. Isolation of a bacterium and demonstration of its role in other respiratory disease. N Engl J Med 297:1197-1203, 1977 CrossrefMedlineGoogle Scholar3. CHANDLERHICKLINBLACKMON FMJ: Demonstration of the agent of Legionnaires' disease in tissue. N Engl J Med 297:1218-1220, 1978 CrossrefGoogle Scholar4. KASS E: Legionnaires' disease (editorial). N Engl J Med 297:1229-1230, 1978 CrossrefGoogle Scholar5. JONESHEBERT GG: "Legionnaires'." The Disease, the Bacterium and Methodology. Atlanta, Center for Disease Control, October 1978 Google Scholar6. SABIN A: "Stained slide" microscopic agglutination test. Application to (1) rapid typing of pneumococci, (2) determination of antibody. Am J Pub Health 19:1148-1150, 1929 Google Scholar7. SABIN A: Immediate pneumococcus typing directly from sputum by the Neufeld reaction. JAMA 100:1584-1586, 1933 CrossrefGoogle Scholar8. HODGESFASSSASLAW GRS: Central nervous system disease associated with Mycoplasma pneumoniae infection. Arch Intern Med 130:277-282, 1972 CrossrefMedlineGoogle Scholar9. DINGLEFINLAND JM: Virus pneumonias. II. Primary atypical pneumonias of unknown etiology. N Engl J Med 227:378-385, 1942 CrossrefGoogle Scholar10. FINLANDDINGLE MJ: Virus pneumonias. I. Pneumonias associated with known non-bacterial agents: influenza, psittacosis and Q fever. N Engl J Med 227:342-350, 1942 CrossrefGoogle Scholar11. EDITORIAL: The virus of the so-called "virus pneumonias." N Engl J Med 228:729-731, 1943 CrossrefGoogle Scholar12. EATONMEIKELJOHNVAN HERICKTALBOT MGWJ: Infectious agent from cases of atypical pneumonia apparently transmissible to cotton rats. Science 96:518-519, 1942 CrossrefMedlineGoogle Scholar13. PETERSONHAMFINLAND OTM: Cold agglutinins (autohemagglutinins) in primary atypical pneumonia. Science 97:167, 1943 CrossrefMedlineGoogle Scholar14. EATONMEIKELJOHNVAN HERICK MGW: Studies on the etiology of primary atypical pneumonia; a filterable agent transmissible to cotton rats, hamsters and chick embryos. J Exp Med 79:649-668, 1944 CrossrefMedlineGoogle Scholar15. MARMIONHERSCLYDECHANOCKMUFSONSOMERSONCOUCH BJWRHNR: The mycoplasma (PPLO) agents. Am Rev Respir Dis 88 (Part II):198-239, 1963 Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Boston City Hospital; Boston, Massachusetts PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byLegionellosisCase 39-1983LegionellosisAtlanta to Patient 1 April 1979Volume 90, Issue 4Page: 710-713KeywordsLegionellosis Issue Published: 1 April 1979 PDF downloadLoading ...
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Maxwell Finland (1979) studied this question.
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