Key result
In patients with STEMI undergoing primary PCI, an elevated baseline CRP/albumin ratio and the presence of ≥2 vascular lesions (OR 2.009) were independent predictors of in-hospital mortality.
Why the study?
It was unknown whether baseline serum CRP/albumin ratio is associated with infarct localization, number of vascular lesions, and in-hospital mortality in patients undergoing primary PCI for STEMI.
Does the baseline CRP/albumin ratio predict in-hospital mortality and the number of vascular lesions in patients undergoing primary PCI for STEMI?
Observational (n=116)
No
Does the baseline CRP/albumin ratio predict in-hospital mortality and the number of vascular lesions in patients undergoing primary PCI for STEMI?
An elevated baseline CRP/albumin ratio and the presence of multiple vascular lesions are independent predictors of in-hospital mortality in patients undergoing primary PCI for STEMI.
Answers are grounded in this paper and cite their sources.
Elevated CRP/albumin ratio and multiple vascular lesions were associated with in-hospital mortality after STEMI PCI; hypothesis-generating and should not yet change practice.
Background/aim: This study investigated whether baseline serum level of C-reactive protein (CRP)/albumin ratio is associated with infarct localization, number of vascular lesions, and in-hospital mortality in patients undergoing primary percutaneous coronary intervention (PCI) for acute ST elevation myocardial infarction (STEMI). Methods: The study population consisted of 116 patients diagnosed with STEMI. The CRP/albumin ratio at first admission, cardiac troponin-I (cTnI), PCI results, and clinical outcomes were recorded. Results: The mean CRP/albumin ratio, cTnI level, and mean number of vascular lesions were significantly higher in non-survivors than in survivors (p = 0.006, p = 0.004, and p = 0.007, respectively). Multivariate logistic regression analysis demonstrated that the CRP/ albumin ratio and number of coronary artery lesions were independent predictors of mortality in STEMI patients. According to these analyses, the presence of ≥ 2 vessel lesions was the most important predictor of mortality, with an odds ratio of 2.009 (95% confidence interval: 1.191–3.387, p = 0.009). Conclusion: This study demonstrates the potential utility of the CRP/albumin ratio for predicting the clinical outcome of patients with STEMI. In addition, the presence of ≥ 2 vascular lesions contributed to a 2-fold increase in mortality rate in STEMI patients.
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Söğüt et al. (2021) conducted an observational in ST-segment elevation myocardial infarction (STEMI) (n=116). Elevated CRP/albumin ratio and ≥ 2 vascular lesions vs. Lower CRP/albumin ratio and 0-1 vascular lesions was evaluated on In-hospital mortality (OR 2.009, 95% CI 1.191-3.387, p=0.009). In patients with STEMI undergoing primary PCI, an elevated baseline CRP/albumin ratio and the presence of ≥2 vascular lesions (OR 2.009) were independent predictors of in-hospital mortality.
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