Key result
Isolated cTnI elevation >0.45 ng/mL after PCI was not independently associated with increased all-cause mortality after adjusting for baseline risk factors (adjusted HR 1.45; 95% CI 0.86-2.46; P=0.162).
Why the study?
Does isolated cTnI elevation after PCI predict all-cause mortality in patients with normal CK-MB?
Population
2,362 patients who underwent percutaneous coronary intervention with normal CK-MB and cTnI values at…
Comparison
Isolated elevation of cardiac troponin I after PCI vs Normal cTnI after PCI
Design
Cohort
Follow-up
2 years
Authors
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Isolated post-PCI cTnI elevation warrants no management change; leaves open its incremental prognostic value beyond baseline risk.
Cohort (n=2,362)
Yes
Does isolated cTnI elevation after PCI predict all-cause mortality in patients with normal CK-MB?
Hazard Ratio: 1.45 (95% CI 0.86–2.46)
Absolute Event Rate: 4.5% vs 2.7%
p-value: p=0.162
Isolated cTnI elevation after PCI in the absence of CK-MB rise is associated with a modestly increased risk of death, but this is largely driven by baseline clinical risk factors rather than the troponin elevation itself.
Cavallini et al. (2010) conducted a cohort in Percutaneous coronary intervention (PCI) (n=2,362). Isolated cTnI elevation >0.45 ng/mL after PCI vs. Normal cTnI was evaluated on All-cause mortality (HR 1.45, 95% CI 0.86-2.46, p=0.162). Isolated cTnI elevation >0.45 ng/mL after PCI was not independently associated with increased all-cause mortality after adjusting for baseline risk factors (adjusted HR 1.45; 95% CI 0.86-2.46; P=0.162).
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