November 1, 1990Archives of Internal Medicine

Increased Prescribing of Antidepressants Subsequent to ß-Blocker Therapy

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Why the study?

Does beta-blocker therapy increase the incidence of antidepressant use in patients treated for chronic diseases?

Structured PICO

Does beta-blocker therapy increase the incidence of antidepressant use in patients treated for chronic diseases?

Population

Patients receiving new prescriptions for beta-blockers or other treatments for chronic diseases (diuretics, antihypertensives, and hypoglycemics) during 1984, with no use in the previous 6 months. Includes 3,218 new beta-blocker users.

Intervention

Beta-blocker therapy (propranolol, other lipophilic, or hydrophilic beta-blockers)

Comparator

Other treatments for chronic diseases (diuretics, antihypertensives, hypoglycemics) or no study drug use (reference group)

Outcome

Incidence of antidepressant use initiated within 12 months after the study drugsafety

Discussion

No takes yet. Share an insight, caveat, or question.

Implication

Propranolol use is associated with a significantly higher risk of subsequent antidepressant prescription compared to other beta-blockers or other chronic disease medications.

Cite This Study

B Thiessen (1990) studied this question.

synapsesocial.com/papers/6a857e4f6e0f1d231d202da2 https://doi.org/10.1001/archinte.1990.00390220044009

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Implication

Propranolol use is associated with a significantly higher risk of subsequent antidepressant prescription compared to other beta-blockers or other chronic disease medications.

Increased Prescribing of Antidepressants Subsequent to ß-Blocker Therapy

Structured PICO

Discussion

Implication

Cite This Study

Increased Prescribing of Antidepressants Subsequent to ß-Blocker Therapy

Structured PICO

Discussion

Implication

Cite This Study

Also Consider

Also Consider